Our understanding of the sphingolipidoses has improved as a result of the investigation of molecular mechanisms causing clinical heterogeneity. This knowledge, derived from both the protein and gene structures, should bring therapy for these inherited disorders closer to a realistic possibility.

Two unique aspects of spinoza's theory of freedom of expression are explored in depth-Its articulation of a positive liberty of expression, And the distinction it draws between pure expressive acts and speech intended as action. Spinoza's theory is then applied to cases where speech causes harm. His theory is explicitly distinguished from that of mill, And it is concluded that his theory, Although not without faults, Avoids several difficulties of other liberal theories.

The purpose of this paper is to enter the conversation about stakeholder theory with the goal of clarifying certain foundational issues. I want to show, along with Boatright, that there is no stakeholder paradox, and that the principle on which such a paradox is built, the Separation Thesis, is nicely self-serving to business and ethics academics. If we give up such a thesis we find there is no stakeholder theory but that stakeholder theory becomes a genre that is quite rich. (...) It becomes one of many ways to blend together the central concepts of business with those of ethics. Rather than take each concept of business singly or the whole of “business” together and hold it to the light of ethical standards, we can use the stakeholder concept to create more fine-grained analyses that combine business and ethics; or more simply, we can tell many more, and more interesting, stories about business. (shrink)

This special issue presents developments in research on the cognitive mechanisms and consequences of surprise. Amidst much progress, surprise research has often been siloed, so, as editors, we have sought to juxtapose insights, theories, and findings, to support cross‐fertilization in future research. The present paper sets the stage by presenting a historical summary, highlighting contrasts in definitions, and tracing major threads running through this issue and the larger surprise literature.

Visual aids can improve comprehension of risks associated with medical treatments, screenings, and lifestyles. Do visual aids also help decision makers accurately assess their risk comprehension? That is, do visual aids help them become well calibrated? To address these questions, we investigated the benefits of visual aids displaying numerical information and measured accuracy of self-assessment of diagnostic inferences (i.e., metacognitive judgment calibration) controlling for individual differences in numeracy. Participants included 108 patients who made diagnostic inferences about three medical tests on (...) the basis of information about the sensitivity and false-positive rate of the tests and disease prevalence. Half of the patients received the information in numbers without a visual aid, while the other half received numbers along with a grid representing the numerical information. In the numerical condition, many patients --especially those with low numeracy-- misinterpreted the predictive value of the tests and profoundly overestimated the accuracy of their inferences. Metacognitive judgment calibration mediated the relationship between numeracy and accuracy of diagnostic inferences. In contrast, in the visual aid condition, patients at all levels of numeracy showed high-levels of inferential accuracy and metacognitive judgment calibration. Results indicate that accurate metacognitive assessment may explain the beneficial effects of visual aids and numeracy --a result that accords with theory suggesting that metacognition is an essential part of risk literacy. We conclude that well-designed risk communications can inform patients about health-relevant numerical information while helping them assess the quality of their own risk comprehension. (shrink)

Many philosophers appeal to intuitions to support some philosophical views. However, there is reason to be concerned about this practice as scientific evidence has documented systematic bias in philosophically relevant intuitions as a function of seemingly irrelevant features (e.g., personality). One popular defense used to insulate philosophers from these concerns holds that philosophical expertise eliminates the influence of these extraneous factors. Here, we test this assumption. We present data suggesting that verifiable philosophical expertise in the free will debate-as measured by (...) a reliable and validated test of expert knowledge-does not eliminate the influence of one important extraneous feature (i.e., the heritable personality trait extraversion) on judgments concerning freedom and moral responsibility. These results suggest that, in at least some important cases, the expertise defense fails. Implications for the practice of philosophy, experimental philosophy, and applied ethics are discussed. (shrink)

Evaluational internalism holds that only features internal to agency (e.g., motivation) are relevant to attributions of virtue [Slote, M. (2001). Morals from motives. Oxford: Oxford University Press]. Evaluational externalism holds that only features external to agency (e.g., consequences) are relevant to attributions of virtue [Driver, J. (2001). Uneasy virtue. Cambridge: Cambridge University Press]. Many evaluational externalists and internalists claim that their view best accords with philosophically naïve (i.e., folk) intuitions, and that accordance provides argumentative support for their view. Evaluational internalism (...) and externalism are incompatible views and therefore it is impossible that both views are supported by most folk intuitions. In four experiments, we present evidence that neither pure evaluational internalism nor pure evaluational externalism accurately capture some relevant folk intuitions about virtue. However, our experiments suggest external factors are vastly more important than internal factors for folk attributions of virtue. While these data do not entail that evaluational internalism and externalism about virtue are false, they situate important argumentative burdens, constrain philosophical theory about virtue, and illustrate a valuable method that could foster more efficient progress in ethics. (shrink)

In this paper I first argue that when answering the question of whether or not governments may restrict emigration, Brock and Blake are staking out positions not astronomically far from one another. Despite the ostensibly large philosophical gap between the two, both think that certain governments may restrict emigration when such restriction is agreed to in a morally binding contract. Secondly, both authors think that there are specific “circumstances” or “conditions” under which a contract that restricts emigration can be morally (...) binding. This second part of the paper will pose some questions that explore these various circumstances or conditions. The ultimate aim of the paper is to help point the debate in the right direction so as to further develop an answer to the question of whether or not governments may restrict emigration. (shrink)

Ideas of wilderness in North America are evolving toward some new configuration. Current wilderness ideology, among other weaknesses, has been charged with encouraging a radical separation between people and nature and with being inadequate to serve the protection of biodiversity. Sustainable development and “wise use” privatization of wildlands have been offered as alternatives to the Western wilderness concept. I review this wilderness debate and argue that critical distinctions between wildness and wilderness and self and other must be settled before alternatives (...) can be considered. I look closely at arguments for sustainable development and argue that the limits on the human use of nature are discounted and technological management of wildlands is emphasized. I also argue that the “wise use” response to wilderness is a radically utilitarian option that does not contribute to evolving ideas of wilderness or sustainability and that replacing the sustainable development idea with sustainable landscape protection might better serve both wildness and human projects. Finally, I offer the ways of life of post-migratory ecosystem-based cultures as models of appropriate human behavior within a management framework of habitat protection for viable populations of all native species and conclude that our purpose in protecting wildness is not to preserve nature or to improve it, but rather to learn a sense of limits from it and to model culture after it. (shrink)

Studies in philosophy: I. Tufts, J.H. On moral evolution. II. Willcos, W.F. The expansion of Europe in its influence upon population. III. Woods, R.A. Democracy a new unfolding of human power. IV. Sharp, F.C. An analysis of the moral judgment. V. Woodbridge, F.J.E. The problem of consciousness. VI. Norton, E.L. The intellectual element in music. VII. Raub, W.L. Pragmatism and Kantianism. VIII. Lyman, E.W. The influence of pragmatism upon the status of theology.--Studies in psychology: IX. Delabarre, E.B. Influence of surrounding (...) objects on the apparent direction of a line. X. Swift, E.J. Beginning a language; a contribution to the psychology of learning. XI. Pierce, A.H. An appeal from the prevailing doctrine of a detached subconsciousness. XII. Woodworth, R.S. The cause of a voluntary movement. XIII. Burnett, C.T. An experimental test of the classical theory of volition. (shrink)

Winfield’s explication of Hegel’s theory of mind, especially Hegel’s theory of intelligence, is, he suggests, important for solving three problems that continue to haunt contemporary work in the philosophy of mind and epistemology: 1) A problem concerning the acquisition of language and its place in an account of consciousness, 2) A problem concerning the objectivity of representations, and 3) A problem concerning the grounds of knowing. I think Winfield is correct in identifying all three problems as having their source in (...) Kantian philosophy. I examine these three problems more carefully through a critical lens aimed at recent work by John McDowell and Robert Brandom. Both philosophers claim certain Hegelian influences. I argue that, in crucial ways, both Brandom and McDowell have each inherited the problems Hegel sought to solve and that are so clearly articulated in Winfield’s essay. (shrink)

Use of the word "Counter-Enlightenment" has become increasingly frequent in scholarly and journalistic writing. The word was almost certainly invented by the late Sir Isaiah Berlin, and it is owing to his enormous prestige and on-going influence that it has gained its current familiarity. In Berlin's view, two of the most important sources of the supposed Counter-Enlightenment are J. G. Hamann and J. G. Herder. But as I show, Berlin's numerous accounts of their thought are profoundly flawed and reflect not (...) Herder's or Hamann's own thought, but rather that of late nineteenth- and early twentieth-century German historians, who wished to legitimate their own anti-democratic, and hence anti-Enlightenment, ideology through the construction of a false historical genealogy. (shrink)

The article focuses on a passage from Carl Schmitt?s Ex Captivitate Salus - a book famously written in a Nurnberg prison in 1946 - in which he draws, from memory, on a story derived from Serbian epic poetry, to justify his understanding of historiography, victory, and the figure of the hero. Analyzing the entire Serbian epic poem from which Schmitt extracts the vignette in question, we show how the text of the poem presents a significantly more complicated and messy picture (...) of the figures of victor, victory, and hero, heroism. The anonymous Serbian poet, addressing himself to his contemporary audience, with which he is intimately familiar, really subverts simplistic expectations regarding the heroism and victory of the Serbian hero, Marko Kraljevic. Finally, the article contrasts these complex and at times paradoxical figures of victory and the hero in the poem with their presentation in Carl Schmitt?s writing. (shrink)

According to many contemporary metaphysicians, we ought to theorize in terms of grounding because of its promise to explicate the idea of reality having a layered structure. However, a tension emerges when one combines the layered structure view with the view that higher-level facts are not reducible to lower-level facts. This tension emerges from two problems. The first problem arises from the fact that grounding explanations entail true universal generalizations. In order to satisfy this constraint, we will face serious pressure (...) to make sure the entities involved in the grounded facts are appropriately connected to the entities involved in the grounding facts, otherwise the generalizations associated with those grounding claims will come out false. However, ensuring the appropriate connections seemingly leaves no way for the non-reductivist to fully squeeze out reference to higher-level entities as we descend the levels of ground. This threatens the result that some higher-level facts must be taken as fundamental, which the non-reductivist cannot accept. -/- I argue that we can resolve the tension by taking the connections at issue to be essentially true. We can call this view essentialist non-reductivism. One significant upshot of the argument is that we can see not only that essentialist non-reductivism successfully resolves the tension, but that in principle no better solution could be offered. (shrink)

Starting from the assumption that working memory capacity is an important predictor of general fluid intelligence, we asked which aspects of working memory account for this relationship. Two theoretical stances are discussed. The first one posits that the important explanatory factor is storage capacity, roughly defined as the number of chunks possible to hold in the focus of attention. The second one claims that intelligence is explained by the efficiency of executive control, for instance, by prepotent response inhibition. We investigated (...) 96 children at the age between 10 and 13. They completed a version of the n-back task that allows assessment of both storage capacity and inhibitory control. They also completed Raven’s Progressive Matrices as the fluid intelligence test and the Test for Creative Thinking - Drawing Production, for control purposes. We found that Raven’s scores correlated negatively with the number of unnecessary responses to irrelevant stimuli but they did not correlate with the number of signal detections. We conclude that children’s fluid intelligence depends on inhibitory control, with no relationship with storage capacity. (shrink)

I examine in this paper deification and demonisation – the social attribution of absolute ‘Good’ and ‘Evil’ to individuals or individual entities. Specifically, I unpack ways that evilness and goodness have become personified in the figure of the chief executive officer in contemporary, particularly US, business culture. Showing both the readily accessible and widely used nature of these religious tropes, I nevertheless argue that both deification and demonisation have ethically and politically disempowering effects for organisational members, the wider citizenry, and (...) for critique within the field of business ethics. (shrink)

Hilbert’s choice operators τ and ε, when added to intuitionistic logic, strengthen it. In the presence of certain extensionality axioms they produce classical logic, while in the presence of weaker decidability conditions for terms they produce various superintuitionistic intermediate logics. In this thesis, I argue that there are important philosophical lessons to be learned from these results. To make the case, I begin with a historical discussion situating the development of Hilbert’s operators in relation to his evolving program in the (...) foundations of mathematics and in relation to philosophical motivations leading to the development of intuitionistic logic. This sets the stage for a brief description of the relevant part of Dummett’s program to recast debates in metaphysics, and in particular disputes about realism and anti-realism, as closely intertwined with issues in philosophical logic, with the acceptance of classical logic for a domain reflecting a commitment to realism for that domain. Then I review extant results about what is provable and what is not when one adds epsilon to intuitionistic logic, largely due to Bell and DeVidi, and I give several new proofs of intermediate logics from intuitionistic logic+ε without identity. With all this in hand, I turn to a discussion of the philosophical significance of choice operators. Among the conclusions I defend are that these results provide a finer-grained basis for Dummett’s contention that commitment to classically valid but intuitionistically invalid principles reflect metaphysical commitments by showing those principles to be derivable from certain existence assumptions; that Dummett’s framework is improved by these results as they show that questions of realism and anti-realism are not an “all or nothing” matter, but that there are plausibly metaphysical stances between the poles of anti-realism and realism, because different sorts of ontological assumptions yield intermediate rather than classical logic; and that these intermediate positions between classical and intuitionistic logic link up in interesting ways with our intuitions about issues of objectivity and reality, and do so usefully by linking to questions around intriguing everyday concepts such as “is smart,” which I suggest involve a number of distinct dimensions which might themselves be objective, but because of their multivalent structure are themselves intermediate between being objective and not. Finally, I discuss the implications of these results for ongoing debates about the status of arbitrary and ideal objects in the foundations of logic, showing among other things that much of the discussion is flawed because it does not recognize the degree to which the claims being made depend on the presumption that one is working with a very strong logic. (shrink)

The domain of Islamic thought and intellectual history boasts an important body of studies relevant to the Arabic philosophy of language, as well as a growing interest in Islamicate argumentation theory and practice. There remains, however, a dearth of volumes which pool research from both areas and examine them together. Filling this gap is more critical than ever. In our time, significant work is being conducted in argumentation theory, but little of it draws from, or relates to, the rich i...

The post-classical genre of the “protocols for dialectical inquiry and disputation” has its more proximate origins in the famed Risāla of Shams al-Dīn al-Samarqandī. The greater part of his conceptions and methodology, however, consists in a streamlining and universalizing of the more strictly juristic dialectic of his teacher Burhān al-Dīn al-Nasafī ; and this in turn draws on the highly logicized dialectic of Rukn al-Dīn al-ʿAmīdī and his teacher Raḍī al-Dīn al-Nīsābūrī. At the heart of methods in this lineage, and (...) carried forward by al-Samarqandī into the universal ādāb al-baḥth, are three truth-preserving logical relationships critical to the truth-seeking enterprise of dialectic: entailment, mutual negation or exclusion, and causal concomitance. The practical elaboration of these relations reveals a logic in action—a premodern dialogical logic for living disputation praxis. In fact, so critical were these to the dialectical enterprise that al-Samarqandī devoted a specialized treatise entirely to summarizing their defining features and rules, aptly naming it the ʿAyn al-Naẓar, or “Wellspring of Rational Investigation.” In this article, and drawing upon a recently published digital critical edition, I will present an analytical outline of these core logical relations as presented in the ʿAyn al-Naẓar. Then I will address a number of points of interest in this text, grouped under six themes: the potential for cross-disciplinary advancement; notions in discursive development; significant or uniquely contributive formulations; peculiarities of content; signs of an evolving, universalist agenda; and evidence that the ʿAyn al-Naẓar was designed as an aide-mémoire for the active disputant. (shrink)

In this article, I explore the importance of Giorgio Agamben’s theory of potentiality for rethinking education. While potentiality has been a long-standing concern for educational practitioners and theorists, Agamben’s work is unique in that it emphasizes how potentiality can only be thought of in relation to impotentiality. This moment of indistinction—what I refer to as im-potential—has important implications. First, I argue that if potentiality and impotentiality are separated from one another, the result is a stratified educational system where some students (...) are commanded to actualize their potentiality in the form of standardized tests while others are abandoned by the system. Second, thinking im-potentiality enables us to move beyond problematic formulations of learning and rediscover the uniqueness of studying. Here, I offer a brief example of study through an analysis of ‘Tinkering Schools’, an alternative program founded by Gever Tulley in San Francisco. And finally, without a concept of im-potentiality, the discourse of the ‘child genius’ becomes commodified as a power to be harnessed and actualized in the name of neoliberal entrepreneurialism. Only through a return to im-potentiality can we reclaim Genius and its relationship to the question of educational freedom. (shrink)

In lieu of an abstract, here is a brief excerpt of the content:Cartesian Skepticism from Bare PossibilityRobert WachbritIn making his case for skepticism, Peter Unger offers the following exotic case as one which “conforms to a familiar, if not often explicitly artic-ulated pattern or form” of skeptical reasoning: 1 imagine that there is an evil scientist who deceives subjects into falsely believing that there are rocks. Living in a world bereft of rocks, he induces belief in their existence using electrodes (...) implanted into the appropriate parts of the subjects’ brai ns, protoplasm, or systems through which he sends patterns of electrical impulses in accord with his deceptive designs. Unger then offers the following argument, which is supposed to instantiate the pattern or form of this kind of skeptical reasoning:If you know that there are rocks, then you can know that there is no such scientist doing this to you. But no one can ever know that there is no evil scientist who is, by means of electrodes, deceiving him into falsely believing there to be rocks. So... you never know that there are rocks. But of course we have chosen our person, and the matter of there being rocks, quite arbitrarily, and this argument... may be generalized to cover any external matter at all. From this, we may conclude... that nobody knows anything about the external world. 2After presenting this case and articulating its form, Unger claims that “this argument is the same in form as the ‘evil demon’ argument in Descartes’s [End Page 109] Meditations; it is but a more modern, scientific counter-part, with its domain of application confined to matters concerning the external world.” He then proceeds to describe Descartes’s argument as “the most compelling sceptical argument the phil osophical literature has to offer,” calling it in fact “the classical argument for scepticism.” 3These claims may seem a little bit surprising; for it is not obvious, even from the most careful attention to the text, that what is written about the evil demon in the First Meditation constitutes a skeptical argument at all, and the scholarly literature is generally, and perhaps surprisingly, quite confusing about just what is going on at the end of the First Meditation. Further, rather than being exceedingly compelling as Unger thinks, arguments of this form are not only assiduously avoided by Descarte s during his descent into skepticism but are in fact, as I shall argue with some help from Descartes, weak and considerably less compelling than the kind of skeptical challenges Descartes actually offers.My purpose in this paper, then, is to make two related points, one historical and the other philosophical. First, I will try to demonstrate, on the basis of both textual and critical evidence, that Descartes was not offering a (further and final) skeptica l argument when he invented his demon. I will try to exhibit some of the confusions in the scholarly literature about the text of the last three paragraphs of the First Meditation and, by so doing, support Gouhier’s position that the idea of the demon “ha s no metaphysical significance; it is purely a methodological artifice which permits doubt to continue....” 4 Second, I will show that embodied in Descartes’s rejection of this kind of skeptical reasoning is the very reason for its weakness, a weakness that should prevent it from being considered, as Unger considers it, the classical form of skeptical argument. The inventions of the First Meditation still exercise considerable hold on our philosophical imaginations. I hope to show that, at least as far as the demon is concerned, Descartes would have been surprised at some of the most conventional and entrenched scholarly interpretations given his use of it and not at all sympathetic to its employment in a skeptical argument. Lest the demon seem an old and tired subject of philosophical scrutiny, let me beg the reader’s indulgence by promising both a deeper than usual look into the text of the end of the First Meditation and some significant conclusions about Cartesian skepticism that are hardly commonplace and thus neither old nor tired. [End Page 110]I. The Textual EvidenceThe demon makes its first appearance in the last paragraph of the... (shrink)

Ethical training in graduate programs is an important part of the professional development process. Such training has taken a position of prominence in both counseling and clinical psychology but seems to be lagging behind in the field of sport psychology. A debate exists about whether such training is necessary and, if so, how it should be provided. An important step in better understanding these issues is to identify how such training is currently taking place. This study surveyed the program directors (...) of sport psychology programs listed in the Directory of Graduate Programs in Applied Sport Psychology (Burke, Sachs, & Schrader, 2002) about the ethical training that takes place in their programs and their perceptions of the preparedness of the students in their programs. Of those contacted, 54% (n = 47) responded to the e-mail based survey. The results from these respondents indicated that 64.4% of programs require training in ethics and that the training was most commonly integrated into other nonethics courses. Overall, respondents did not feel as if students were completely prepared for either the ethical or legal issues that they will face in their professional careers. The importance of ethical training and suggestions for improving ethical training are discussed. (shrink)

BackgroundEthics review is the process of assessing the ethics of research involving humans. The Ethics Review Committee (ERC) is the key oversight mechanism designated to ensure ethics review. Whether or not this governance mechanism is still fit for purpose in the data-driven research context remains a debated issue among research ethics experts.Main textIn this article, we seek to address this issue in a twofold manner. First, we review the strengths and weaknesses of ERCs in ensuring ethical oversight. Second, we map (...) these strengths and weaknesses onto specific challenges raised by big data research. We distinguish two categories of potential weakness. The first category concerns persistent weaknesses, i.e., those which are not specific to big data research, but may be exacerbated by it. The second category concerns novel weaknesses, i.e., those which are created by and inherent to big data projects. Within this second category, we further distinguish between purview weaknesses related to the ERC’s scope (e.g., how big data projects may evade ERC review) and functional weaknesses, related to the ERC’s way of operating. Based on this analysis, we propose reforms aimed at improving the oversight capacity of ERCs in the era of big data science.ConclusionsWe believe the oversight mechanism could benefit from these reforms because they will help to overcome data-intensive research challenges and consequently benefit research at large. (shrink)

In this paper, I will argue that the experiential-based approaches of Edmund Husserl’s phenomenology and William James’s radical empiricism can help inform an account of humanism more rooted in concrete experience. Specifically, I will outline a form of humanism closely connected to the conceptual similarities between James’s radical empiricism and the general character of Husserl’s phenomenology of experience. Whereas many forms of humanism are underscored by an eliminativist impulse, I sketch a humanism of lived-experience more motivated by the restrictive and (...) experiential impetus closer to pragmatism and phenomenology than humanism defended on metaphysically eliminativist grounds.This paper is organized in the following way. In the first section, I explain the general character of Husserl’s phenomenology and explain the methodological commitments that underscore his concept of experience. In the second section, I outline the conceptual similarities between James’s later radical empiricism and Husserl’s thought. Finally, in the third section, James’s critique of metaphysics and his radical empiricism allow for a limited acceptability of religious interests in experience as well as scientific interests. These interests result from how we experience the world and affirm freedom and individuality of every person’s lived-experience. (shrink)

Delilci kötülük argümanları, teizme karşı sunulan en güçlü argümanların başında gelmektedir. Bu argümanlar arasında gereksiz ve anlamsız kötülük türlerini merkeze alan argümanlar özellikle önemlidir. Edward H. Madden ve Peter Hare gereksiz kötülük üzerine bir argüman formüle ederken, William Rowe anlamsız kötülük üzerine argümanlar geliştirmiştir. Madden ve Hare argümanlarını altmışlarda, Rowe ise yetmişlerde öne sürmüş olsalar da İslam düşüncesinde gereksiz ve anlamsız kötülük kavramına ışık tutabilecek bir teori bulunmaktadır. Bu tür kötülükleri açıklamak için öne sürdüğüm teori, ivaz teorisidir. Bu makalede (...) ivaz teorisinin nedensiz ve anlamsız kötülükleri nasıl açıklayabileceğini inceleyeceğim. (shrink)

Presents an analysis of Jonathan Edwards' theological position. This book includes a study of his life and the intellectual issues in the America of his time, and examines the problem of free will in connection with Leibniz, Locke, and Hume.